e.g. We live in a large house in a large suburb as I earn a large salary.
Great = very large e.g. There has been a great change in the size of the population in that area.
Big = extensive in size and importance e.g. They are having a big wedding with high-profile guests.
Substantial/Considerable = extensive in size, amount, form or importance e.g. The company has given considerable thought to its marketing campaign.
Major = extensive in size or importance e.g. Building that highway is a major project and the government is investing heavily in it.
Enormous = huge e.g. The diamond on her wedding ring is enormous.